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休診日 消化管外科
火・木・土・日・祝
ほか,年末年始
小児外科
水・金・土・日・祝
ほか,年末年始

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診療案内係:059-232-1111(内線5206)

時間外:059-232-1111(5233)

住所

〒514-8507
三重県津市江戸橋2丁目174

研究業績

2018年

英文業績(PubMed)

Pub-Med

01

Weng W, Liu N, Toiyama Y, Kusunoki M, Nagasaka T, Fujiwara T, Wei Q, Qin H, Lin H, Ma Y, Goel A. Novel evidence for a PIWI-interacting RNA (piRNA) as an oncogenic mediator of disease progression, and a potential prognostic biomarker in colorectal cancer. Mol Cancer. 2018 Jan 30; 17(1): 16.

02

Muraki Y, Mizuno S, Nakatani K, Wakabayashi H, Ishikawa E, Araki T, Taniguchi A, Isaji S and Okuda M. Monitoring of peripheral blood cluster of differentiation 4+ adenosine triphosphate activity and CYP3A5 genotype to determine the pharmacokinetics, clinical effects and complications of tacrolimus in patients with autoimmune diseases. Exp Ther Med. 2018 Jan; 15(1): 532–538.

03

Yamada A, Yu P, Lin W, Okugawa Y, Boland CR, Goel A. A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancer. Sci Rep. 2018 Jan 12; 8(1): 575.

04

Shimura T, Toiyama Y, Hiro J, Imaoka H, Fujikawa H, Kobayashi M, Ohi M, Inoue Y, Mohri Y, Kusunoki M. Monitoring perioperative serum albumin can identify anastomotic leakage in colorectal cancer patients with curative intent. Asian J Surg. 2018 Jan; 41(1): 30-38.

05

Araki T, Hashimoto K, Okita Y, Fujikawa H, Kondo S, Kobayashi M, Ohi M, Toiyama Y, Inoue Y, Uchida K, Mohri Y, Kusunoki M. Colonic Histological Criteria Predict Development of Pouchitis after Ileal Pouch: Anal Anastomosis for Patients with Ulcerative Colitis. Dig Surg. 2018; 35(2): 138-143.

06

Seo S, Miyake H, Hock A, Koike Y, Yong C, Lee C, Li B, Pierro A. Duhamel and Transanal Endorectal Pull-throughs for Hirschsprung' Disease: A Systematic Review and Meta-analysis. Eur J Pediatr Surg. 2018 Feb; 28(1): 81-88.

07

Hock AM, Chen Y, Miyake H, Koike Y, Seo S, Pierro A. Initiation of Enteral Feeding After Necrotizing Enterocolitis. Eur J Pediatr Surg. 2018 Feb; 28(1): 44-50.

08

Okugawa Y, Shirai Y, Toiyama Y, Saigusa S, Hishida A, Yokoe T, Tanaka K, Tanaka M, Yasuda H, Fujikawa H, Hiro J, Kobayashi M, Araki T, Inoue Y, McMillan DC, Kusunoki M, Miki C. Clinical Burden of Modified Glasgow Prognostic Scale in Colorectal Cancer. Anticancer Res. 2018 Mar; 38(3): 1599-1610.

09

Otake K, Uchida K, Kubo M, Yamamoto A, Nagano Y, Uratani R, Hashimoto K, Matsushita K, Inoue M, Sawada H, Kusunoki M. Clinical factors associated with in-hospital death in pediatric surgical patients admitted to the neonatal intensive care unit: a 15-year single tertiary center experience. J Pediatr Surg. 2018 Mar; 53(3): 499-502.

10

Kobayashi T, Hisamatsu T, Suzuki Y, Ogata H, Andoh A, Araki T, Hokari R, Iijima H, Ikeuchi H, Ishiguro Y, Kato S, Kunisaki R, Matsumoto T, Motoya S, Nagahori M, Nakamura S, Nakase H, Tsujikawa T, Sasaki M, Yokoyama K, Yoshimura N, Watanabe K, Katafuchi M, Watanabe M, Hibi T. Predicting outcomes to optimize disease management in inflammatory bowel disease in Japan: their differences and similarities to Western countries. Intest Res. 2018 Apr; 16(2): 168-177.

11

Okugawa Y, Yao L, Toiyama Y, Yamamoto A, Shigemori T, Yin C, Omura Y, Ide S, Kitajima T, Shimura T, Fujikawa H, Yasuda H, Hiro J, Yoshiyama S, Kobayashi M, Tanaka K, Inoue Y, Araki T, Miki C, Kusunoki M. Prognostic impact of sarcopenia and its correlation with circulating miR-21 in colorectal cancer patients. Oncol Rep. 2018 Apr; 39(4): 1555-1564.

12

Koi M, Okita Y, Carethers JM. Fusobacterium nucleatum Infection in Colorectal Cancer: Linking Inflammation, DNA Mismatch Repair and Genetic and Epigenetic Alterations. J Anus Rectum Colon. 2018; 2(2): 37-46.

13

Uchino M, Ikeuchi H, Sugita A, Futami K, Watanabe T, Fukushima K, Tatsumi K, Koganei K, Kimura H, Hata K, Takahashi K, Watanabe K, Mizushima T, Funayama Y, Higashi D, Araki T, Kusunoki M, Ueda T, Koyama F, Itabashi M, Nezu R, Suzuki Y; a research grant on intractable disease affiliated with the Japan Ministry of Health Labor Welfare. Pouch functional outcomes after restorative proctocolectomy with ileal-pouch reconstruction in patients with ulcerative colitis: Japanese multi-center nationwide cohort study. J Gastroenterol. 2018 May; 53(5): 642-651.

14

Okumura A, Ida S, Mori M, Shimizu T; Committee on Pediatric Nutrition of The Japanese Pediatric Society (Uchida K included as one of corporate authors). Attitudes of pediatricians toward Children's consumption of ionic beverages. BMC Pediatr. 2018 May 25; 18(1): 176.

15

Okumura A, Ida S, Mori M, Shimizu T; Committee on Pediatric Nutrition of the Child Health Consortium of Japan (Uchida K included as one of corporate authors).Vitamin B1 Deficiency Related to Excessive Soft Drink Consumption in Japan. J Pediatr Gastroenterol Nutr. 2018 May; 66(5): 838-842.

16

Takesue Y, Kusachi S, Mikamo H, Sato J, Watanabe A, Kiyota H, Iwata S, Kaku M, Hanaki H, Sumiyama Y, Kitagawa Y, Nakajima K, Ueda T, Uchino M, Mizuguchi T, Ambo Y, Konosu M, Ishibashi K, Matsuda A, Hase K, Harihara Y, Okabayashi K, Seki S, Hara T, Matsui K, Matsuo Y, Kobayashi M, Kubo S, Uchiyama K, Shimizu J, Kawabata R, Ohge H, Akagi S, Oka M, Wakatsuki T, Suzuki K, Okamoto K, Yanagihara K. Antimicrobial susceptibility of common pathogens isolated from postoperative intra-abdominal infections in Japan. J Infect Chemother. 2018 May; 24(5): 330-340.

17

Miyake H, Li B, Lee C, Koike Y, Chen Y, Seo S, Pierro A. Liver damage, proliferation, and progenitor cell markers in experimental necrotizing enterocolitis. J Pediatr Surg. 2018 May; 53(5): 909-913.

18

Miyake H, Chen Y, Hock A, Seo S, Koike Y, Pierro A. Are prophylactic anti-reflux medications effective after esophageal atresia repair? Systematic review and meta-analysis. Pediatr Surg Int. 2018 May; 34(5): 491-497.

19

Shigeyasu K, Okugawa Y, Toden S, Miyoshi J, Toiyama Y, Nagasaka T, Takahashi N, Kusunoki M, Takayama T, Yamada Y, Fujiwara T, Chen L, Goel A. AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer. JCI Insight. 2018 Jun 21; 3(12).

20

Toiyama Y, Okugawa Y, Boland CR, Goel A. Reply. Gastroenterology. 2018 Jun; 154(8): 2274-2275.

21

Ikeuchi H, Uchino M, Sugita A, Futami K, Fukushima K, Hata K, Koganei K, Kusunoki M, Uchida K, Nezu R, Kimura H, Takahashi K, Kameyama H, Higashi D, Koyama F, Ueda T, Mizushima T, Suzuki Y. Long-term outcomes following restorative proctocolectomy ileal pouch - anal anastomosis in pediatric ulcerative colitis patients: Multicenter national study in Japan.Ann Gastroenterol Surg. 2018 Jul 27; 2(6):428-433.

22

Umeno J, Esaki M, Hirano A, Fuyuno Y, Ohmiya N, Yasukawa S, Hirai F, Kochi S, Kurahara K, Yanai S, Uchida K, Hosomi S, Watanabe K, Hosoe N, Ogata H, Hisamatsu T, Nagayama M, Yamamoto H, Abukawa D, Kakuta F, Onodera K, Matsui T, Hibi T, Yao T, Kitazono T, Matsumoto T; CEAS study group. Clinical features of chronic enteropathy associated with SLCO2A1 gene: a new entity clinically distinct from Crohn's disease. J Gastroenterol. 2018 Aug; 53(8): 907-915.

23

Okugawa Y, Toiyama Y, Ichikawa T, Kawamura M, Yasuda H, Fujikawa H, Saigusa S, Ohi M, Araki T, Tanaka K, Inoue Y, Tanaka M, Miki C, Kusunoki M. Colony-stimulating factor-1 and colony-stimulating factor-1 receptor co-expression is associated with disease progression in gastric cancer. Int J Oncol. 2018 Aug; 53(2): 737-749.

24

Okugawa Y, Toiyama Y, Oki S, Ide S, Yamamoto A, Ichikawa T, Kitajima T, Fujikawa H, Yasuda H, Saigusa S, Hiro J, Yoshiyama S, Kobayashi M, Araki T, Kusunoki M. Feasibility of Assessing Prognostic Nutrition Index in Patients With Rectal Cancer Who Receive Preoperative Chemoradiotherapy. Int J Oncol. 2018 Aug; 53(2): 737-749.

25

Koike Y, Li B, Chen Y, Miyake H, Lee C, Chi L, Wu R, Inoue M, Uchida K, Kusunoki M, Delgado-Olguin P, Pierro A. Live Imaging of Fetal Intra-abdominal Organs Using Two-Photon Laser-Scanning Microscopy. Methods Mol Biol. 2018; 1752: 63-69.

26

Kondo S, Araki T, Okita Y, Yamamoto A, Hamada Y, Katsurahara M, Horiki N, Nakamura M, Shimoyama T, Yamamoto T, Takei Y, Kusunoki M. Colitis with wall thickening and edematous changes during oral administration of the powdered form of Qing-dai in patients with ulcerative colitis: a report of two cases. Clin J Gastroenterol. 2018 Aug; 11(4): 268-272.

27

Toiyama Y, Okugawa Y, Kondo S, Okita Y, Araki T, Kusunoki K, Uchino M, Ikeuchi H, Hirota S, Mitsui A, Takehana K, Umezawa T, Kusunoki M. Comprehensive analysis identifying aberrant DNA methylation in rectal mucosa from ulcerative colitis patients with neoplasia. Oncotarget. 2018 Sep 4; 9(69): 33149-33159

28

Inoue M, Uchida K, Nagano Y, Matsushita K, Koike Y, Otake K, Okita Y, Toiyama Y, Araki T, Kusunoki M. Impact of relationship between the stoma site and the primary incision on occurrence of laparotomy wound infection in contaminated or dirty wound operations in neonates. Pediatr Surg Int. 2018 Sep; 34(9): 957-960.

29

Kondo S, Araki T, Toiyama Y, Tanaka K, Kawamura M, Okugawa Y, Okita Y, Saigusa S, Inoue Y, Uchida K, Mohri Y, Kusunoki M. Downregulation of trefoil factor-3 expression in rectum is associated with the development of ulcerative colitis-associated cancer. Oncol Lett. 2018 Sep; 16(3): 3658-3664.

30

Toiyama Y, Oki S, Okugawa Y, Ide S, Yasuda H, Fujikawa H, Yoshiyama S, Hiro J, Ohi M, Inoue Y, Araki T, Kusunoki M. Clinical Impact of Preoperative Albumin-Globulin Ratio in Patients with Rectal Cancer Treated with Preoperative Chemoradiotherapy. Oncology. 2018; 95(5): 270-280.

31

Morishita T, Hishida A, Okugawa Y, Morimoto Y, Shirai Y, Okamoto K, Momokita S, Ogawa A, Tanaka K, Nishikawa R, Toiyama Y, Inoue Y, Sakurai H, Urata H, Tanaka M, Miki C. Polymorphisms in folic acid metabolism genes do not associate with cancer cachexia in Japanese gastrointestinal patients. Nagoya J Med Sci. 2018 Nov; 80(4): 529-539.

32

Inoue M, Uchida K, Ichikawa T, Nagano Y, Matsushita K, Koike Y, Okita Y, Toiyama Y, Araki T, Kusunoki M. Contaminated or dirty wound operations and methicillin-resistant Staphylococcus aureus (MRSA) colonization during hospitalization may be risk factors for surgical site infection in neonatal surgical patients. Pediatr Surg Int. 2018 Nov; 34(11): 1209-1214.

33

Inoue M, Nakashima R, Enomoto M, Koike Y, Zhao X, Yip K, Huang SH, Waldron JN, Ikura M, Liu FF, Bratman SV. Plasma redox imbalance caused by albumin oxidation promotes lung-predominant NETosis and pulmonary cancer metastasis. Nat Commun. 2018 Nov 30; 9(1): 5116

34

Okugawa Y, Toiyama Y, Yamamoto A, Shigemori T, Yin C, Narumi A, Omura Y, Ide S, Kitajima T, Fujikawa H, Yasuda H, Hiro J, Yoshiyama S, Kobayashi M, Araki T, McMillan DC, Miki C, Kusunoki M. Clinical Impact of Muscle Quantity and Quality in Colorectal Cancer Patients: A Propensity Score Matching Analysis. JPEN J Parenter Enteral Nutr. 2018Nov; 42(8): 1322-1333.

35

Toiyama Y, Okugawa Y, Fleshman J, Richard Boland C, Goel A. MicroRNAs as potential liquid biopsy biomarkers in colorectal Cancer: A systematic review. Biochim Biophys Acta Rev Cancer. 2018 Dec; 1870(2): 274-282.

36

Okugawa Y, Toiyama Y, Shigeyasu K, Yamamoto A, Shigemori T, Yin C, Ichikawa T, Yasuda H, Fujikawa H, Yoshiyama S, Hiro J, Ohi M, Araki T, Kusunoki M, Goel A. Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer. J Transl Med. 2018 Dec 18; 16(1): 366.

37

Hishida A, Okugawa Y, Miki C. No substantial effect of polymorphisms in CPT1B and CPT2 on plasma carnitine levels in Japanese. Nagoya journal of medical science. Dec 2018, 81(3).

Non-Pub-Med

01

Ohi M, Saigusa S, Ichikawa T, Yasuda H, Yoshiyama S, Fujikawa H, Okita Y, Yoshiyama S, Hiro J, Toiyama Y, Araki T, Kusunoki M. Partial sternotomy for secure esophagogastric anastomosis in esophageal cancer surgery. Journal of Surgery. Volume 2018; Issue01.

和文業績

著書

01

内田恵一:第6章 疾患別の栄養法,C. 消化管異常,日本小児栄養消化器肝臓学会(編),小児臨床栄養学,診断と治療社,改訂第2版,224-226,2018.10.31

02

内田恵一:第9章 静脈・経腸栄養,A. 静脈栄養 1. 末梢静脈栄養,日本小児栄養消化器肝臓学会(編),小児臨床栄養学,診断と治療社,改訂第2版,369-375,2018.10.31

03

問山裕二:Ⅵ章 治療法各論 下部消化管疾患 急性虫垂炎,佐々木 裕(編),最新ガイドライン準拠 消化器疾患 診断・治療指針,中山書店,東京,338-341,2018.7

04

井上幹大:第5章 症候と鑑別診断,C. 腹痛,日本小児栄養消化器肝臓学会(編),診断と治療社,改訂第2版,114-116,2018.10.31

総説

05

内田恵一,井上幹大,小池勇樹,松下航平,楠 正人:【炎症性腸疾患(第2版)-病因解明と診断・治療の最新知見-】 小児・高齢炎症性腸疾患の特徴と対応および炎症性腸疾患患者の妊娠への指導 小児炎症性腸疾患に対する外科治療の適応と問題点.日本臨床.76(3): 507-512, 2018

06

内田恵一,荒木俊光,井上幹大,小池勇樹,松下航平,長野由佳,近藤 哲,大北喜基,問山裕二,楠 正人:【特集 各種小児消化管ストーマ作成の適応と術式・合併症】 炎症性腸疾患における腸管ストーマ造設.小児外科.50(9):925-928,2018

07

荒木俊光,問山裕二,大北喜基,廣 純一郎,楠 正人:【炎症性腸疾患(第2版)-病因解明と診断・治療の最新知見-】 炎症性腸疾患のがん化 潰瘍性大腸炎に合併した直腸・肛門管癌の外科治療.日本臨床.76(3):556-559, 2018

08

荒木俊光,近藤 哲,大北喜基,廣 純一郎,問山裕二,楠 正人:【消化器外科50の術式別術後ケアイラストブック 手術の流れからケアのなぜ?が見える!わかる!】 (2章)下部消化管の手術10 虫垂切除術.消化器外科Nursing.2018 秋季増刊:87-90,2018

09

荒木俊光,近藤 哲,大北喜基,廣 純一郎,問山裕二,楠 正人:【消化器外科50の術式別術後ケアイラストブック 手術の流れからケアのなぜ?が見える!わかる!】 (2章)下部消化管の手術10 痔核手術.消化器外科Nursing.2018 秋季増刊:91-94,2018

10

荒木俊光,近藤 哲,大北喜基,廣 純一郎,問山裕二,楠 正人:【消化器外科50の術式別術後ケアイラストブック 手術の流れからケアのなぜ?が見える!わかる!】 (2章)下部消化管の手術10 腸閉塞解除術.消化器外科Nursing.2018 秋季増刊:95-98,2018

11

荒木俊光,近藤 哲,大北喜基,廣 純一郎,問山裕二,楠 正人:【消化器外科50の術式別術後ケアイラストブック 手術の流れからケアのなぜ?が見える!わかる!】 (2章)下部消化管の手術10 炎症性腸疾患の手術. 消化器外科Nursing.2018 秋季増刊:99-102,2018

12

荒木俊光、大北喜基、近藤 哲、潮田美規、奥川彩子、濱田あゆみ、林 智世、楠 正人:【炎症性腸疾患のストーマ造設とストーマケア】 クローン病の肛門病変のskin careの実際とストーマが必要となる病態.WOC Nursing. 6(10):40-47, 2018

13

井上幹大:【特集 技術認定取得医が解説する基礎的内視鏡外科手術】腹腔鏡下人工肛門造設術.小児外科.50(12):1233-1235,2018

14

廣 純一郎,問山裕二,藤川裕之,楠 正人:【閉塞性大腸癌-ベストプラクティスを探す】閉塞性大腸癌に対するステント留置 根治切除不能閉塞性大腸癌のマネジメント ステント留置 versus 外科治療. 臨床外科.73(1):28-31, 2018

15

廣 純一郎,荒木俊光,楠 正人:【特集 炎症性腸疾患アップデート-いま外科医に求められる知識と技術】潰瘍性大腸炎の手術手技 腹腔鏡下大腸全摘・回腸嚢肛門(管)吻合術.臨床外科.73(12): 1350-1355, 2018

16

大北喜基,大井正貴,小林美奈子,荒木俊光,問山裕二,内田恵一,楠 正人:【最新の外科感染症対策】 腹腔ドレーン.消化器外科.41(12):1677-1682,2018

17

藤川裕之,北嶋貴仁,廣 純一郎,問山裕二,楠 正人:【手術で臓器が「どうなる?」から術後ケアが見える!わかる!イラスト理解 消化器外科の術式・術後ケア】 直腸切除術.消化器外科Nursing.23(8):704-708, 2018

18

北嶋貴仁,藤川裕之,廣 純一郎,問山裕二,楠 正人:【手術で臓器が「どうなる?」から術後ケアが見える!わかる!イラスト理解 消化器外科の術式・術後ケア】 結腸切除術.消化器外科Nursing. 23(8):699-703, 2018

原著

19

荒木俊光,大北喜基,近藤 哲,問山裕二,楠 正人:消化管吻合法バイブル. 2章 小腸・結腸・直腸領域 炎症性腸疾患 11狭窄形成術. 監修 北島政樹, 医学書院, 第1版第1刷:134-138,2018

20

大井正貴,楠 正人:消化管吻合法バイブル.総論 漏れない,狭窄しない吻合法の概念 3 縫合しの種類と使用法. 監修 北島政樹, 医学書院, 第1版第1刷:11-17,2018

症例報告

21

山本 晃,井上幹大,長野由佳,松下航平,大竹耕平,内田恵一,楠 正人:茎捻転が原因と考えられた新生児メッケル憩室穿孔の1例. 日本小児外科学雑誌. 54(2):253-258, 2018

その他

22

問山 裕二, 奥川 喜永, 田中 光司, 荒木 俊光, 内田 恵一, 菱田 朝陽, 内野 基, 池内 浩基, 廣田 誠一, 楠 正人, C Richard Boland, Goel Ajay: microRNA メチル化パネルを用いた潰瘍性大腸炎癌化リスク診断 〔Review from ─ Gastroenterology 2017;153:1634-1646.e8〕. INTESTINE. 22巻4号 pp.379-382, 2018.7