山崎  英俊
(2006年11月10日現在)


 ■英文
1. Potential of dental mesenchymal cells in developing teeth.
H. Yamazaki, M. Tsuneto, M. Yoshino, K. Yamamura, S-I. Hayashi. Stem cells (in press) (2006)
2. Constant rate of steady-state self-antigen trafficking from skin to regional lymph node. M. Yoshino, H. Yamazaki, LD. Shultz, S-I. Hayashi. Int. Immunol. 18 1541-1548 (2006)
3. Presence and distribution of neural crest-derived cells in the murine developing thymus and their potential for differentiation.
H. Y amazaki, E. Sakata, T. Yamane, A. Yanagisawa, K. Abe, K. Yamamura, S-I. Hayashi and T. Kunisada. Int. Immunol. 17: 549-58. (2005)
4. Suppression of progressive loss of coat color in microphthalmia-vitiligo mutant mice.
K. Kurita, M. Nishito, H. Shimogaki, K. Takada , H. Yamazaki and T. Kunisada T. J Invest Dermatol. 125(3):538-44.(2005)
5. Ascorbic acid promotes osteoclastogenesis from embryonic stem cells. M. Tsuneto,
H. Yamazaki, M.Yoshino, T.Yamada and S-I. Hayashi. Biochem Biophys Res Commun. 335(4):1239-46.(2005).
6. Enforced expression of PU.1 rescues osteoclastogenesis from embryonic stem cells lacking tal-1.
M. Tsuneto, A. Tominaga, H. Yamazaki, M. Yoshino, S. Orkin and S-I. Hayashi. Stem Cell. 23:134-43. (2005)
7. Cooperative and indispensable roles of endothelin 3 and KIT signalings in melanocyte development.
H. Aoki, T. Motohashi, N. Yoshimura, H. Yamazaki, T. Yamane, J.J. Panthier and T. Kunisada T. Dev Dyn. 233:407-17. (2005)
8. Neural Crest Stem Cells and Organogenesis(Chapter VI). In “Trends in Stem Cell Research”
Yamazaki, H., Yoshino, M., and Hayashi, S. Ed. Erik V. Greer. p147-167. Nova Science Publisher, Inc. (2005).
9. Contribution of neural crest cells in the tooth development and the possibility of tooth regeneration.
H. Yamazaki and S-I. Hayashi. J. Oral. Biosci. 46(6): 509-518 (2004).
10. Migration of dendritic cells determines divergent immune responses.
M. Yoshino, H. Yamazaki and S-I. Hayashi. Recent Res. Develop. Biophys. Biochem. 4: 29-48. (2004)
11. Osteoclast Lineage (Chapter 27). In " Handbook of Embryonic Stem Cells".
T. Yamane, H. Okuyama, M. Tsuneto, H. Hemmi, H. Yamazaki and S-I. Hayashi.:, Eds. R.P. Lanza, J.D. Gearhart, B.L.M. Hogan, R.D. McKay, D.A. Melton, R. Pedersen, J.A. Thomson, and M.D. West, Academic Press, San Diego, CA. (2004)
12. Lipopolysaccharide-induced osteoclastogenesis in Src homology 2-domain phosphatase-1-deficient viable motheaten mice.
S. Hayashi, M. Tsuneto, T. Yamada, M. Nose, M. Yoshino, LD. Shultz and H. Yamazaki. Endocrinology. 145(6):2721-9.(2004)
13. Developmental changes of Ni (2+) sensitivity and automaticity in Nkx2.5-positive cardiac precursor cells from murine embryonic stem cell.
K. Manabe, J. Miake, N. Sasaki, H. Furuichi, S. Yano, E. Mizuta, Y. Yamamoto, Y. Hoshikawa, H. Yamazaki, F. Tajima, G. Shiota, E. Nanba, S. Ohgi, K. Hidaka, T. Morisaki, Y. Kurata, JK. Lee, O. Igawa, C. Shigemasa and I. Hisatome. Circ J. 68(7):724-6.(2004)
14. Soluble c-kit receptor mobilizes hematopoietic stem cells to peripheral blood in mice.
Y. Nakamura, F. Tajima, K. Ishiga, H. Yamazaki, M. Oshimura, G. Shiota and Y. Murawaki. Exp Hematol. 32(4):390-396. (2004)
15. Retinoic acid receptor  dominant negative form causes steatohepatitis and liver tumor in transgenic mice.
A. Yanagitani, S. Yamada, S. Yasui, T. Shimomura, R. Murai, T.Kanbe, T. Saeki, M. Ichiba, Y. Tanabe, S. Morino, A. Kurimasa, N. Usuda, H. Yamazaki, T. Kunisada, H. Ito, Y. Murawaki and G. Shiota. Hepatology. 40(2):366-75. (2004)
16. Tooth development and tooth regeneration using tooth germ, dental pulp cells, neural crest cells and embryonic stem cells.
H. Yamazaki, T. Kurino, E. Sakata, M. Yoshino and S.I. Hayashi. Recent Res. Develop. Biophys. Biochem. 3: 907-925. (2003)
17. In vitro differentiation of mouse ES cells into hematopoietic, endothelial, and osteoblastic cell lineages: the possibility of in vitro organogenesis.
M. Tsuneto, T. Yamane, H. Okuyama, H. Yamazaki and S.I. Hayashi. Methods Enzymol. 365:98-114. (2003)
18. Generation of structures formed by lens and retinal cells differentiating from embryonic stem cells.
M. Hirano, A. Yamamoto, N. Yoshimura, T. Tokunaga, T. Motohashi, K. Ishizaki, H. Yoshida, K. Okazaki, H. Yamazaki, S.I. Hayashi and T. Kunisada. Dev Dyn. 228(4):664-71. (2003)
19. Discrete types of osteoclast precursors can be generated from embryonic stem cells.
H. Okuyama, M. Tsuneto, T. Yamane, H. Yamazaki and S.I. Hayashi. Stem cells, 21: 670-680 (2003)
20. Distinct osteoclast precursors in the bone marrow and extramedullary organs characterized by responsiveness to Toll-like receptor ligands and TNF-a.
S.I. Hayashi, T. Yamada, M. Tsuneto, T. Yamane, M. Takahashi, L.D. Shultz and H. Yamazaki. J. Immunol. 171: 5130-5139 (2003).
21. Distinct antigen trafficking from skin in the steady and active states.
M. Yoshino, H. Yamazaki, H. Nakano, T. Kakiuchi, K. Ryoke, T. Kunisada and S.I. Hayashi. Int. Immunol., 15: 773-779 (2003).
22. Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells.
T. Yamada, H. Yamazaki, T. Yamane, M. Yoshino, H. Okuyama, M. Tsuneto, T. Kurino, S.I. Hayashi and S. Sakano. Blood, 101(6):2227-2234 (2003).
23. Reduction of osteoclast in a critical embryonic period is essential for inhibition of mouse tooth eruption.:
M. Yoshino, H. Yamazaki, H. Yoshida, S. Niida, S.I. Nishikawa, K. Ryoke, T. Kunisada and S.I. Hayashi. J. Bone. Miner. Res., 18:108-116 (2003).
24. Clonotypic analysis of T cells accumulating at arthritic lesions in HTLV-I env-pX transgenic rats.
T. Sugaya, A. Ishizu, H. Ikeda, Y. Nakamaru, K. Fugo, M. Higuchi, H. Yamazaki, K. Imai and T. Yoshiki, T. Exp. Mol. Pathol., 72:56-61 (2002).
25. Requirement for MD-1 in cell surface expression of RP105/CD180 and B cell responsiveness to lipopolysaccharide.
Y. Nagai, R. Shimazu, H. Ogata, S. Akashi, K. Sudo, H. Yamazaki, S.I. Hayashi, Y. Iwakura, M. Kimoto and K. Miyake.
Blood. 99:1699-1705 (2002).
26. Development of osteoclast lineage cells.
H. Okuyama, H.Yamazaki, T. Yamane and S.I. Hayashi. Research Advances in Blood. (Global Research Network), 1: 75-84 (2001).
27. Immunological hyperresponsiveness in HTLV-I LTR-env-pX transgenic rats: a prototype animal model for collagen vascular and HTLV-I-related inflammatory diseases.
Y. Nakamaru, A. Ishizu, H. Ikeda, T. Sugaya, K. Fugo, M. Higuchi, H. Yamazaki and T. Yoshiki. Pathobiology. 69:11-18.(2001)
28. Skinantigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-b1-dependent cells.
H. Hemmi, M. Yoshino, H. Yamazaki, M. Naito, T. Iyoda, Y. Omatsu, S. Shimoyama, J.J. Letterio, T. Nakabayashi, H. Tagaya, T. Yamane, M. Ogawa, S.I. Nishikawa, K. Ryoke, K. Inaba, S.I. Hayashi and T. Kunisada. Int. Immunol., 13: 695-704 (2001).
29. Temporal and spatial localization of osteoclasts in colonies from embryonic stem cells.
H. Hemmi, H. Okuyama, T. Yamane, S. Nishikawa, T. Nakano, H. Yamazaki, T. Kunisada and S. Hayashi. Biochem. Biophys. Res. Commun., 280(2):526-534 (2001).
30. Presence of osteoclast precursors in colonies cloned in the presence of hematopoietic colony-stimulating factors.
H. Yamazaki, T. Kunisada, Y. Yamane and S. I. Hayashi. Exp. Hematol., 29(1):68-76 (2001).
31. Wnt signaling regulates hemopoiesis through stromal cells.
T. Yamane, T. Kunisada, H. Tsukamoto, H. Yamazaki, H. Niwa, S. Takada and S.I. Hayashi. J. Immunol., 167(2):765-772 (2001).
32. Ligands for receptor tyrosine kinases expressed in the skin as environmental factors for melanocyte development.
T. Kunisada, H. Yamazaki, and S.I. Hayashi. J. Invest. Dermatol. Symp. Proc., 6: 6-9 (2001).
33. Characterization of a novel member of the FGFR family, HrFGFR, in Halocynthia roretzi.
S. Kamei, I. Yajima, H. Yamamoto, A. Kobayashi, K.W. Makabe, H. Yamazaki, S.I. Hayashi and T. Kunisada. Biochem. Biophys. Res. Commun., 275: 503-508 (2000).
34. Sequential requirements for SCL/tal-1, GATA-2, macrophage colony-stimulating factor, and osteoclast differentiation factor/osteoprotegerin ligand in osteoclast development.
T. Yamane, T. Kunisada, H. Yamazaki, T. Nakano, S. H. Orkin and S.I Hayashi. Exp. Hematol., 28(7):833-840 (2000).
35. Keratinocyte expression of transgenic hepatocyte growth factor affects melanocyte development, leading to dermal melanocytosis.
T. Kunisada, H. Yamazaki, T. Hirobe, S. Kamei, M. Omoteno, H. Tagaya, H. Hemmi, U. Koshimizu, T. Nakamura and S.I. Hayashi. Mech. Dev., 94: 67-78 (2000).
36. Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.
H. Tagaya, T. Kunisada, H. Yamazaki, T. Yamane, T. Tokuhisa, E.F. Wagner, T. Sudo, L.D. Shultz and S.I. Hayashi. Blood, 95(11):3363-3370 (2000).
37. Accelerated growth of hepatocytes in association with Up-regulation of cyclin E in transgenic mice expressing the dominant negative form of retinoic acid receptor. A. Tsutsumi, G. Shiota,
H. Yamazaki, T. Kunisada, T. Terada and H. Kawasaki. Biochem. Biophys. Res. Commun., 278: 229-235 (2000).
38. Derivation of melanocytes from embryonic stem cells in culture. T. Yamane, S.I. Hayashi, M. Mizoguchi, H. Yamazaki and T. Kunisada. Dev. Dyn., 216 :450-458 (1999).
39. Tooth-specific expression conferred by the regulatory sequences of rat dentin sialoprotein gene in transgenic mice. H.Yamazaki, T. Kunisada, A. Miyamoto, H. Tagaya and S.I. Hayashi.
Biochem. Biophys. Res. Commun., 260: 433-440 (1999).
40. CD9 molecule expressed on stromal cells is involved in osteoclastogenesis. Y. Tanio, H. Yamazaki, T. Kunisada, K. Miyake and S.I. Hayashi. Exp. Hematol., 27: 853-859 (1999).
41. Transgene expression of steel factor in the basal layer of epidermis promotes
survival, proliferation, differentiation and migration of melanocyte precursors.
T. Kunisada, H. Yoshida, H. Yamazaki, A. Miyamoto, H. Hemmi, E. Nishimura, L.D. Shultz, S.I. Nishikawa and S.I. Hayashi. Development, 125: 2915-2923. (1998).
42. Establishment and characterization of an immortal macrophage-like cell line inducible
to differentiate to osteoclasts. A. Miyamoto, T. Kunisada, H. Hemmi, T. Yamane, H. Yasuda, K. Miyake, H. Yamazaki and S.I. Hayashi. Biochem. Biophys. Res. Commun., 242: 703-709 (1998).
43. Promotion of early osteoclastogenesis and B lymphopoiesis in the bone marrow
of transgenic rats with the env-pX gene of human T-cell lymphotropic virus type I.
H.Yamazaki, T. Kunisada, A. Ishizu, H. Ikeda, I. Miyoshi, T. Sudo, S.I. Hayashi and T. Yoshiki. Oncogene, 17: 2955-2960 (1998).
44. Commitment and differentiation of stem cells to the osteoclast lineage. S.I. Hayashi, T. Yamane, A. Miyamoto, H. Hemmi, H. Tagaya, Y. Tanio, H. Kanda, H. Yamazaki and
T. Kunisada. Biochem. Cell Biol., 76: 911-922 (1998).
45. Establishment and characterization of pro-B cell lines from motheaten mutant mouse defective in SHP-1 protein tyrosine phosphatase. A. Miyamoto, T. Kunisada, H. Yamazaki, K. Miyake, S.I. Nishikawa, T. Sudo, L.D. Shultz and S.I. Hayashi.
Immunol. Let., 63: 75-82 (1998).
46. HTLV-I env-pX transgenic rats: prototype animal model for collagen vascular diseases.
H. Yamazaki, H. Ikeda, A. Ishuzu, H. Shikishima, K. Kikuchi, A. Wakisaka, M. Hatanaka and T. Yoshiki. Leukemia. 11: Suppl 3: 258-259 (1997).
47. Development of osteoclasts from embryonic stem cells through a pathway that is c-fms, but not c-kit dependent. T. Yamane, T. Kunisada, H. Yamazaki, T. Era, T. Nakano and S.I. Hayashi. Blood, 90: 3516-3523 (1997).
48. Osteoclast precursors in bone marrow and peritoneal cavity. S.I. Hayashi, A. Miyamoto, T. Yamane, H. Kataoka, M. Ogawa, S. Sugawara, S. Nishikawa, S.I. Nishikawa, T. Sudo, H. Yamazaki and T. Kunisada. J. Cell. Physiol., 170: 241-247 (1997).
49. A wide spectrum of collagen vascular and autoimmune diseases in transgenic rats carrying
the env-pX gene of human T-lymphotropic virus type I. H. Yamazaki, H. Ikeda, A. Ishizu, Y. Nakamaru, T. Sugaya, K. Kikuchi, S. Yamada, A. Wakisaka, N. Kasai, T. Koike, M. Hatanaka and T. Yoshiki. Int.immunol., 9:339-346 (1997).
50. HTLV-I pX transgenic rats:development of cytokine-producing mammary carcinomas and establishment of the pX mammary carcinoma cell lines. H. Shikishima, H. Ikeda, S. Yamada, H. Yamazaki, K. Kikuchi, A. Wakisaka, N. Kasai, K, Shimotohno and T. Yoshiki. Leukemia.11: Suppl 3:70-72 (1997).
51. Models of HTLV-I-induced diseases.Infectious transmission of of HTLV-I in inbred rats andHTVL-I env-pX transgenic rats. T. Yoshiki, H. Ikeda, U. Tomaru, N. Kasai, S. Ohya, T. Kasai, I. Yamashita, K. Morita, H. Yamazaki, A. Ishizu, Y. Nakamaru, K. Kikuchi, S. Tanaka and A. Wakisaka. Leukemia.11: Suppl 3:245-246 (1997).
52. Progressive effects of α-phenyl-N-tert-butyl nitrone (PBN) on rat embryo development in vitro. T. Yamashita, H.Yamazaki, Y. Kon, T. Watanabe, J. Arikawa, I. Miyoshi, N. Kasai and M. Kuwabara. Free Rad. Biol. Med., 23: 1073-1077 (1997).
53. Cytokine-producing mammary carcinoma in transgenic rats carrying the pX gene of
human T-lymphotropic virus type I. S. Yamada, H. Ikeda, H. Yamazaki, H. Shikishima, K.
Kikuchi, A. Wakisaka, N. Kasai, K. Shimotohno and T. Yoshiki.
Cancer Res., 55: 2524-2527 (1995).


 ■和文
1. 蟯虫とヒト急性虫垂炎との関係について
clinical parasitology Vol5 No.1 59-62 (1994)
河合薫子、山崎英俊、石倉 浩、八木欣平、佐藤昇志、高橋秀史、菊池浩吉、石倉 肇
2. Development of collagen vascular diseases and production of autoantibodies in HTLV-I env-pX transgenic rats. 山崎英俊 北海道医学学会誌71: 325-343 (1996).
3. SCFトランスジェニックマウス血液・腫瘍科36(4):p338-345.(1998)
邊見弘明、山崎英俊、林 眞一、国貞隆弘
4. HTLV-I env-pXトランスジェニックラットにおける破骨細胞及びB細胞系譜への影響第38回日本リンパ網内系学会誌 Vol.38 .p203-209 (1998). 山崎英俊、宮本顕友、池田 仁、石津明洋、国貞隆弘、林 眞一、吉木 敬
5. HTLV-I 遺伝子導入モデル動物を用いたHTLV-I関連疾患発症機構の解明
上原記念生命科学財団研究報告集Vol.12 p328-331.(1998). 山崎英俊
6. 破骨細胞分化とストローマ細胞: 蛋白核酸酵素Vol 44, No.7.p854-864.(1999).
山崎英俊、林眞一
7. 再生医療をめざした胚性幹(ES)細胞試験管内分化誘導 Jpn. J. Leprosy Vol70p121-126. (2001) 林眞一、山根利之、奥山洋美、山崎英俊
8. ES細胞からの試験管内分化と器官形成.ホルモンと臨床 Vol.51, No.2 p99-103 (2003).林眞一、奥山洋美、経遠智一、山崎英俊
9. 神経堤細胞と器官形成 鶴見大学歯学部顎機能研究センター 第二回公開シンポジウ ムプロシーデイング 別刷:95-97.(2003). 山崎英俊
10. ES細胞から心筋細胞への分化の分子機序:分子心血管病 5:p263-271.
(2004) 三明淳一郎、山崎英俊、久留一郎


 ■著書
1. 著書(共著) 免疫学コア講義(分担執筆)免疫関連細胞:山崎英俊、林 眞一、木本雅夫:p15-28 木本雅夫、坂口薫雄、山下優毅 編集 南山堂 (2002)