Takemoto Lab.

ABOUT US

The activity of proteins that cleverly regulate neurons shows not only simple ON/OFF but also spatiotemporal dynamics such as localization and timing at individual synapses, but the physiological significance of these dynamics is largely unknown. Therefore, our group is developing memory research focusing on the spatiotemporal dynamics of synaptic molecules using the CALI (Chromophore-assisted light inactivation) method and two-photon microscopy imaging. In addition, we are developing novel optical techniques to enable manipulative analysis of a wider variety of molecules. Through these studies, we aim to approach the unknown principles linking each level of the hierarchy from synaptic molecules to behavioral expression, and to create a new field of study in brain science.