研究業績

2024年

• Koizumi G, Hayashi A, Takigawa A, Yamada R, Murata T, Shimizu K, Watanabe M, Arai N.
  Novel Histopathological Findings of Micro Bone Fragments and Epithelial Response in the Oral Mucosa in Bisphosphonate-Related Osteonecrosis of the Jaw.
  J Investig Med High Impact Case Rep. Jan-Dec;12:23247096241258076　2024.

2023年

• Tachinami H, Tomihara K, Yamada SI, Ikeda A, Imaue S, Hirai H, Nakai H, Sonoda T, Kurohara K, Yoshioka Y, Hasegawa T, Naruse T, Niiyama T, Shimane T, Ueda M, Yanamoto S, Akashi M, Umeda M, Kurita H, Miyazaki A, Arai N, Hayashi R, Noguchi M.
  Neutrophil-to-lymphocyte ratio as an early marker of outcomes in patients with recurrent oral squamous cell carcinoma treated with nivolumab.
  Br J Oral Maxillofac Surg. 61(4):320-326. 2023.
• Fujiwara K, Tsuno H, Okabe M, Yoshida T, Imaue S, Tomihara K, Arai N, Noguchi M.
  Clinical Application of Hyperdry Amniotic Membrane in Cleft Palate Repair.
  Cleft Palate Craniofac J. 60(6):701-705. 2023.

2022年

• Kurohara K, Shimizu K, Murata T, Koizumi G, Takigawa A, Nagata K, Okumura K, Arai N.
  Predictive Value of Neutrophil-Lymphocyte Ratio as a Marker in Antiresorptive Agent-Related Osteonecrosis of the Jaw: A Retrospective Analysis.
  Diagnostics. 29:12(8):1836. 2022.
• Kawajiri J, Nagata K,
  Clinical utility of oral management in allogeneic hematopoietic stem cell transplantation recipients: microbiological evidence based on molecular analysis of oral bacteria.
  Support Care Cancer. 30: 757-764, 2022.

2021年

• Shimizu K, Hayashi M, Ito N, Hamada K, Koizumi G, Kurohara K, Arai N.
  Oral Management of a Haematopoietic Stem Cell Transplant Recipient with Chédiak-Higashi Syndrome.
  Case Rep Dent. 9918199. 2021.

2019年

• Kurohara K, Tomomatsu N, Nakakuki K, Arai N, Yoda T.
  Skeletal stability after maxillary step osteotomy compared with original Le Fort I osteotomy during one-year of follow-up.
  Sci Rep. 9: 9742. 2019.
• Murata T, Shimizu K, Kurohara K, Tomeoku A, Koizumi G, Arai N.
  Role of Phosphodiesterase2A in Proliferation and Migration of Human Osteosarcoma Cells.
  Anticancer Res. 39: 6057-6062. 2019.
• Kurohara K, Tomomatsu N, Nakakuki K, Sakuma T, Arai N, Yoda T.
  Treatment of refractory non-union after maxillary osteotomy: A case report.
  J Stomatol Oral Maxillofac Surg. 120: 493-496. 2018.

2018年

• Kurohara K, Tomomatsu N, Nakakuki K, Sakuma T, Arai N, Yoda T.
  Treatment of refractory non-union after maxillary osteotomy: A case report.
  J Stomatol Oral Maxillofac Surg. in press
• Murata T, Kutsuna T, Kurohara K, Shimizu K, Tomeoku A, Arai N.
  Evaluation of a new hydroxyapatite nanoparticle as a drug delivery system to oral squamous cell carcinoma cells.
  Anticancer Res. 38: 6715-6720, 2018.

2016年

• Iwamoto T, Okamoto A, Ishinaga H, Shimizu K, Gayle AA, Arai N, Takeuchi K, Okuda M.
  A novel approach to predict cetuximab-induced hypersensitivity reaction: detection of drug-specific IgE on basophils.
  Cancer Med. 5: 1004-1012, 2016

2015年

• Inoue S, Arai N, Tomihara K, Takashina M, Hattori Y, Noguchi M.
  Extracellular Ca(2+)-dependent enhancement of cytocidal potency of zoledronic acid in human oral cancer cells.
  Eur J Pharmacol. 761 : 44-54, 2015
• Ahmad F, Murata T, Shimizu K, Degerman E, Maurice D, Manganiello V.
  Cyclic Nucleotide Phosphodiesterases: important signaling modulators and therapeutic targets.
  Oral Dis. 21 : e20-e50, 2015

2014年

• Tomihara K, Fuse H, Heshiki W, Takei R, Zhang B, Arai N, Nakamori K, Noguchi M.
  Gemcitabine chemotherapy induces phenotypic alterations of tumor cells that facilitate antitumor T cell responses in a mouse model of oral cancer.
  Oral Oncol. 50 : 457-467, 2014
• Hiramoto K, Murata T, Shimizu K, Morita H, Inui M, Manganiello VC, Tagawa T, Arai N.
  Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells.
  Cell Signal. 26 : 1807-1817, 2014

2013年

• Noto Z, Yoshida T, Okabe M, Koike C, Fathy M, Tsuno H, Tomihara K, Arai N, Noguchi M, Nikaido T.
  CD44 and SSEA-4 positive cells in an oral cancer cell line HSC-4 possess cancer stem-like cell characteristics.
  Oral Oncol. 49 : 787-795, 2013
• Arai N, Inoue S, Tomihara K, Tsuno H, Noguchi M.
  In vitro synergistic effects of zoledronic acid and calcium on viability of human epithelial cells.
  Oral Dis. 2013 Mar;19(2):200-5.
• Morita H, Murata T, Shimizu K, Okumura K, Inui M, Tagawa T.
  Characterization of phosphodiesterase 2A in human malignant melanoma PMP cells.
  Oncol Rep. 29 : 1275-1284, 2013